International Consortium for Cluster Headache Genetics

The International Consortium for Cluster Headache Genetics (CCG) is a global collaboration to uncover the genetic basis of cluster headache and other rare headache disorders

 

 

 

 

Cluster headache – this intense, one-sided headache that is considered one of the most painful conditions known, comes with pain often behind one eye, and lingers for anywhere from 15 minutes to 3 hours. While some get relief from standard treatments, up to 20% don’t see much benefit.

Why do some people suffer from cluster headache, and why do some not respond to the treatment we currently have? We are not entirely sure. There is a lack of understanding about what really drives these headaches. However, genetics seems to play a role. Through genome-wide association studies (GWAS), we are diving deep into millions of genetic variants to pinpoint what makes some more susceptible. By unraveling these genetic ties, we hope to shine a light on the real culprits behind cluster headaches.